Channel Title: Emory University Channel Description: Emory University is recognized internationally as an inquiry-driven, ethically engaged, and diverse community whose members work collaboratively for positive transformation in the world through courageous leadership in teaching, research, scholarship, health care, and social action. The University consists of an outstanding liberal arts college, highly ranked professional schools, and one of the larger and more comprehensive healthcare systems in the Southeast. Emory is enriched by the legacy and energy of Atlanta, whose downtown is located 15 minutes away. There are approximately 12,570 students at Emory, including 6,890 who are pursuing undergraduate degrees in the liberal arts, nursing, or business. <video> Emory Move In Day 2024 Description: Emory students move in for the Fall 2024 Semester! </video> <video> OTT: Annual Celebration: 2024 EmpowHER Award Description: EmpowHER Award Louise Hecker, PhD Dr. Louise Hecker is a prominent researcher in the field of regenerative biology, with a specialty in pulmonology. Her research primarily focuses on understanding the molecular mechanisms underlying lung fibrosis and developing novel therapeutic approaches for treating this debilitating disease. Throughout her career, Dr. Hecker has made significant contributions to the field, particularly in identifying the role of Nox4 (NADPH oxidase-4) in creating scar tissue in the lungs. Dr. Hecker’s goal is to stop Nox4 by developing improved therapies that would help those affected by fibrotic disorders lead longer, healthier lives. Dr. Hecker has received numerous awards and honors for her work, including grants from the National Institutes of Health (NIH) and the U.S. Departments of Defense and Veterans Affairs. She was also named a Distinguished Investigator by the Georgia Research Alliance (GRA) upon joining Emory. In addition, Dr. Hecker has founded two start-up companies related to her research. She has published extensively in peer-reviewed journals and continues to lead innovative research projects aimed at advancing our understanding of pulmonary fibrosis and developing more effective treatments for patients suffering from this condition. More information: https://www.ott.emory.edu/about/annual-celebrations/index.html </video> <video> OTT: Annual Celebration: 2024 Significant Event of the Year Description: Significant Event of the Year ARPA-H Funding, Philip Santangelo, PhD In 2023, Emory University was selected as the inaugural recipient of funding from the Advanced Research Projects Agency for Health (ARPA-H), a new federal agency within the U.S. Department of Health & Human Services. This transformative three-year, $24.8 million cooperative agreement aims to drive groundbreaking health research and catalyze transformative breakthroughs in the field. The focus of ARPA-H was to identify innovative approaches that could prevent, treat, and potentially cure diseases such as cancer, autoimmune disorders, and infectious diseases. These conditions often arise due to dysregulation of the immune system, impairing the body’s ability to control immune responses and leaving patients vulnerable. Dr. Philip Santangelo, a distinguished professor in the Wallace H. Coulter Department of Biomedical Engineering at Emory University and the Georgia Institute of Technology, emerged as a key player in this endeavor. His groundbreaking work centers around a novel class of mRNA-based drugs designed to precisely “turn on or turn off” genes in individual immune cells. By combining mRNA-encoded antigens with gene modulation technology, Dr. Santangelo’s approach aims to radically enhance specific immune responses. In summary, Dr. Santangelo’s pioneering work, supported by ARPA-H, holds the promise of transforming immune modulation and advancing our ability to combat challenging diseases. The collaboration between Emory University and its research partners exemplifies a commitment to innovation and impactful health outcomes. More information: https://www.ott.emory.edu/about/annual-celebrations/index.html </video> <video> The Dean's Scene - Fun Facts About Oxford College Description: Oxford students share fun facts about the college with Dean Ahad. </video> <video> OTT: Annual Celebration: 2024 IDEAward 23 final Description: Inclusivity, Diversity, and Equity Award (IDEAward) Low English Proficiency Nurse Communication Tool, Christina Calamaro, PhD; Michael Fundora, MD; Morgan Greenleaf; Santiago Arconada Alvarez; Wilbur Lam, MD, PhD Although the United States continues to become more diverse, English remains the primary language spoken. For patients with limited language proficiency (LLP), navigating a healthcare system that is predominantly English-speaking can be overwhelming. Today, over 8% of the U.S. population identifies as LLP. A language barrier leads to a greater potential for medical errors, therefore a solution to increase the quality and equity of healthcare for LLP patients is urgently needed. Limited language proficiency patients report lower satisfaction overall with health encounters, and they are less likely to understand medical diagnoses and treatment plans. The inventors propose a novel mobile application that enables the clinical team to communicate using common phrases in the patient’s language, images, as well as real-time translations. The app, designed with a pediatric setting in mind, encourages rapid and accurate communication with families by eliminating the wait for an interpreter to be available. Drs. Calamaro and Fundora developed the app in partnership with the Emory AppHatchery. In the future, the team hopes to expand the app’s use to adult patients. More information: https://www.ott.emory.edu/about/annual-celebrations/index.html </video> <video> Emory College Gate Crossing 2024 Description: For the kick-off to the 2024-2025 school year, members of the Emory College Class of 2028 were ushered onto campus with the third-annual "Gate Crossing." The entire class, wearing Emory T-shirts and waving pennants, walked through the iconic Haygood-Hopkins Gate cheered on the Emory community. With a class of approximately 1,400, it took over 20 minutes for the whole class to pass through the gate! Afterward President Gregory L. Fenves led a Coke Toast on the Quad. </video> <video> Oxford College Organic Farm Celebrates 10 Years Description: The Oxford College of Emory University Organic Farm celebrated its 10th anniversary on October 26, 2024, bringing together faculty, staff, students, alumni, and visitors in town for Family Weekend. </video> <video> OTT: Annual Celebration: 2024 Innovation of the Year Description: Innovation of the Year A Bio-Inspired Skin Interface Method for Continuous Access to Blood for Measurement and Therapy David Myers, PhD; Nicholas Au Yong, PhD; Priscilla Delgado On average, it takes at least 2-3 hours for a physician to receive results from a blood test. Measurements of blood are typically performed by drawing a patient’s blood, sending the blood to a testing lab, with the results being reported to the physician. This delay may sometimes mean life or death depending on how the results affect treatment outcomes. In many instances, quicker results would allow for real-time treatment. There is a need to continually collect blood and measure its components, but the largest challenge to do so is blood clotting. However, systematic clotting inhibitors pose a great risk to the patient. To address this concern, David Myers, PhD, Nicholas Au Yong, PhD; and Priscilla Delgado have developed a wearable, continuous blood collection device. The device will be a patch that allows for continuous collection of blood, preventing blood clotting as well as monitoring of blood-based biomarkers using sensors embedded in the device. More information: https://www.ott.emory.edu/about/annual-celebrations/index.html </video> <video> Emory Songfest 2024 Description: Songfest at Emory University is a beloved annual tradition in which first-year residence halls compete against one another in a song and dance competition. </video> <video> One Trained at Every Game Description: Emory Healthcare and the Atlanta Falcons team up to save lives, by teaching as many people as possible how to do CPR and use an automated external defibrillator (AED). </video> <video> 2024 Dr.Thadhani's State of WHSC Address Description: Dr. Ravi Thadhani, Executive Vice President for Health Affairs at Emory University, delivers his 2024 State of Woodruff Health Sciences Center address. </video> <video> OTT: Annual Celebration: 2024 Corporate Partnership of the Year Description: Corporate Partnership of the Year Honeywell, Wilbur Lam, MD, PhD; Vivien Sheehan, MD, PhD; Christina Caruso, MD; Evelyn Kendall Williams, PhD; Erica Evans; Kirby Fibben Honeywell, a global leader in innovation across multiple industries, had an idea for a COVID-19 diagnostic and needed access to clinical and scientific expertise. At first, they approached the NIH, who recommended the company to Emory. Upon agreement to collaborate with Emory, Honeywell and Wilbur Lam, MD, PhD, and his team began work on the diagnostic. Ultimately, Honeywell pulled the program, but they were still interested in working with Emory. Intrigued by Lam’s and Vivien Sheehan, MD, PhD’s work on sickle cell disease (SCD), Honeywell began anew with a multi-pronged, multi-year partnership to develop multiple diagnostics for SCD. As of now, the team – including not only Lam, Sheehan, and their labs, but also Evelyn Williams, PhD; Christina Caruso, MD; Erica Evans; and Kirby Fibben – is co-developing with Honeywell and jointly filing patents. As the relationship continues, more patents will be filed for their technologies, as Dr. Lam and Honeywell see the potential to develop diagnostics for infectious and cardiovascular diseases in the years to come. More information: https://www.ott.emory.edu/about/annual-celebrations/index.html </video> <video> Oxford College of Emory University Move-In Day 2024 Description: Move-In day highlights with a welcome from Dean Badia Ahad. </video> <video> OTT: Annual Celebration: 2024 Deal of the Year Description: Deal of the Year Allonix Therapeutics – Liver Receptor Homolog-1 (LRH-1) Modulators as Potential Therapeutics for Metabolic, Cancer, and Inflammatory Diseases Eric Ortlund, PhD Human nuclear receptors are a superfamily of ligand-responsive transcription factors that have central roles in cellular function. The ability of nuclear receptors to control gene programs in response to small lipophilic molecules makes them ideal pharmaceutical targets for a wide range of metabolic and neoplastic diseases, with 10–20% of FDA-approved medications currently targeting nuclear receptors. Liver receptor homolog-1 (LRH-1) is a nuclear hormone receptor known to control diverse transcriptional programs in different tissues related to metabolism, inflammation, and cellular proliferation. Discovery of LRH-1 modulators has been difficult, in part due to the tendency for synthetic compounds to bind unpredictably within the lipophilic binding pocket. Dr. Eric Ortlund and his research team using a structure-guided approach, exploited a newly discovered polar interaction to lock agonists in a consistent orientation. This enabled the discovery of the first low nanomolar LRH-1 agonist, one hundred times more potent than the best previous modulator. Since then, the Emory team has developed LRH-1 modulators as potential therapeutics for metabolic, cancer and inflammatory diseases. In 2023, Emory University executed an exclusive high net worth license with Allonix Therapeutics for this technology. More information: https://www.ott.emory.edu/about/annual-celebrations/index.html </video> <video> OTT: Annual Celebration: 2024 Start-Up of the Year Description: Start-Up of the Year KeyStrike, Ýmir Vigfússon, PhD The last 30 years of computer development and cybersecurity have had one constant: it’s easy to hack a computer. The level of sophistication of modern attack tools makes detecting whether a computer has been hacked incredibly difficult. Modern cybersecurity is unable to detect if an end-user is physically sitting at an authorized device, or if it has been compromised by a hacker seeking to gain further access to a remote server. To help address this issue, Ýmir Vigfússon, PhD developed “KeyStrike”, a small USB device that connects to the USB port of a computer. When an end-user enters a key on their keyboard, KeyStrike will forward the keystroke with additional keystrokes. If the server receives a keystroke from the user without the corresponding additional characters, it can be known immediately that the computer may be compromised. Without access to the secret key, the hack would be detected with overwhelming probability. Since KeyStrike was awarded Innovation of the Year at the 2022 Annual Celebration, they haven’t slowed down. They were accepted into and participated in the Berkeley Skydeck program, licensed their IP from OTT, raised $1.3M, obtained customers, and grew the company to 14 employees. More information: https://www.ott.emory.edu/about/annual-celebrations/index.html </video>

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Emory University is recognized internationally as an inquiry-driven, ethically engaged, and diverse community whose members work collaboratively for positive transformation in the world through courageous leadership in teaching, research, scholarship, health care, and social action. The University consists of an outstanding liberal arts college, highly ranked professional schools, and one of the larger and more comprehensive healthcare systems in the Southeast.

Emory is enriched by the legacy and energy of Atlanta, whose downtown is located 15 minutes away. There are approximately 12,570 students at Emory, including 6,890 who are pursuing undergraduate degrees in the liberal arts, nursing, or business.

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