Channel Title: The Brain Docs Channel Description: Brain health for you, your family, and your community with Drs. Dean and Ayesha Sherzai, a unique husband-and-wife team on the cutting edge of brain science. Drs. Sherzai are dedicated to educating people on the simple steps to long-term health and wellness through their work as neurologists, scientists and public health advocates through online writing, videos, and books. There is a tsunami of diseases of the brain such as Alzheimer’s, stroke and Parkinson’s disease permeating our culture. In our own communities and families, we all have known at least one person suffering from these illnesses and in many cases seen the fallout first-hand. There is no treatment for these diseases, and the emotional, financial and social burden is immense, and at this point, lifestyle interventions are the best solution for reducing dementia risk. <video> Hearty Vegetable Stew with Herby Dumplings #recipe #plantbased Description: Hearty Vegetable Stew with Herby Dumplings 🍲 Happy Thanksgiving from Ayesha and Dean! 🍁 </video> <video> How sex affects your brain (with Dr. Nicole Prause) Description: Sexual behaviour expert and data scientist Dr. Nicole Prause explains the links between sexual health and cognitive health. 0:00 What happens in your brain during sex? 1:53 Sex in male vs. female brains 2:56 Challenges of studying sex 4:26 How porn affects your brain 6:42 Sexual health myths In ‘Your Brain On... Sex’, we discuss: • The neurological processes involved with sex, arousal, attraction, and desire • Why studying the cognitive effects of sexual stimuli can be so complicated • How our relationship with sex is altered as we age, and is affected by periods of change like menopause • The neuroscientific differences between masturbation and sex with a partner • The complex debate about pornography consumption, and the need for better sex education • The links between brain health, heart health, mental health, and sexual health • The benefits of good nutrition, exercise, and stress management for sexual health • Motivations and methods for freeing conversations about sex from stigmas and taboos — especially for women HEAR THE PODCAST: Apple: https://podcasts.apple.com/podcast/your-brain-on-sex/id1730984252?i=1000677603196 Spotify: https://open.spotify.com/episode/4cNkJYBUUhpqeLbVsng5Zr?si=3JLjLWu1RAWTwdV_2FKynw ‘Your Brain On...’ is hosted by neurologists, scientists and public health advocates Ayesha and Dean Sherzai. ‘Your Brain On... Sex’ is Episode 1 of Season 4. The ‘Your Brain On’ podcast is supported by... NEURO ACADEMY — an online brain health community with on-demand courses, live coaching, nutritional guidance, and rich conversations: https://neuroacademy.com/ BRAIN HEALTH INSTITUTE — our virtual clinic, offering comprehensive brain health consultations: https://brainhealthinstitute.com/ CONNECT WITH THE BRAIN DOCS: Website: https://thebraindocs.com/ Instagram: https://www.instagram.com/thebraindocs TikTok: https://www.tiktok.com/@thebraindocs </video> <video> How we understand and treat depression is changing #neuroscience #mentalhealth Description: </video> <video> Ketamine, depression, and your brain (with Dr. John Krystal) Description: Dr. John Krystal, Professor of Psychiatry and Neuroscience, explains how and why ketamine is increasingly being used to treat depression. HEAR THE PODCAST: Apple: https://podcasts.apple.com/podcast/your-brain-on-ketamine/id1730984252?i=1000679174697 Spotify: https://open.spotify.com/episode/4pdKly8bEuGiW4dWSUc614?si=jfTxXwTPQOeiFGks40qvYw 0:00 How we discovered ketamine’s antidepressant effects 0:56 How ketamine affects the brain 2:38 Why ketamine’s antidepressant effects could be revolutionary 4:59 Ketamine dosages, explained 7:50 The risks of ketamine In ‘Your Brain On... Ketamine’, we discuss: • The neurochemical mechanisms of ketamine, and its interplay with depression • What we know about the opportunities and pitfalls of using ketamine in mental health treatment • The potential for ketamine use in reducing the impacts of neurodegenerative diseases like Alzheimer’s and Parkinson’s • How technology and improvements in passive and active data collection are helping us better understand how ketamine affects cognition and neuroplasticity • The history of ketamine’s use as an antidepressant • How ketamine is actually administered, through various dosages and courses of treatment ‘Your Brain On...’ is hosted by neurologists, scientists and public health advocates Ayesha and Dean Sherzai. Dr. John Krystal is a Professor of Psychiatry, of Neuroscience, and of Psychology at Yale School of Medicine. His research on ketamine, from the 90s through to today, is foundational in our understanding of the therapeutic and antidepressant effects of ketamine ‘Your Brain On... Ketamine’ is Episode 2 of Season 4. The ‘Your Brain On’ podcast is supported by... NEURO WORLD RETREAT 2025 — our transformative four-day brain health retreat in San Diego, California, taking place 2–5 September 2025: https://neuroworldretreat.com/ NEURO ACADEMY — an online brain health community with on-demand courses, live coaching, nutritional guidance, and rich conversations: https://neuroacademy.com/ BRAIN HEALTH INSTITUTE — our virtual clinic, offering comprehensive brain health consultations: https://brainhealthinstitute.com/ CONNECT WITH THE BRAIN DOCS: Website: https://thebraindocs.com/ Instagram: https://www.instagram.com/thebraindocs TikTok: https://www.tiktok.com/@thebraindocs </video> <video> How treating hearing loss can reduce dementia risk (with Dr. Frank Lin) Description: Dr. Frank Lin, Director of the Cochlear Center for Hearing and Public Health at Johns Hopkins, joins us on the Your Brain On... podcast to discuss: 0:00 The link between hearing loss and dementia 1:03 The history of hearing loss research 1:46 How age affects hearing loss 3:03 How can hearing loss be measured? 5:15 The future of hearing aid technology In ‘Your Brain On... Hearing Loss’, we discuss: • The different kinds and causes of hearing loss • The relationship between aging and hearing loss • The neurological distinction between ‘hearing’ and ‘listening’ • The recent groundbreaking studies which have made the link between hearing loss and cognitive decline clearer than ever • How associated conditions like tinnitus impact the brain • What’s coming next in hearing aid technology ‘Your Brain On’ is hosted by neuroscientists and public health advocates Ayesha and Dean Sherzai. ‘Your Brain On... Hearing Loss’ is Episode 3 of Season 2. HEAR THE PODCAST: Apple: https://podcasts.apple.com/podcast/your-brain-on-hearing-loss/id1730984252?i=1000655639519 Spotify: https://open.spotify.com/episode/2PA5h7I2qAo2GFSgYZJ4LP?si=Pd8GuMCkR3mQFBXuZYkd1g Website (and Crossword): https://thebraindocs.com/your-brain-on/hearing-loss/ The ‘Your Brain On’ podcast is supported by... NEURO ACADEMY — an online brain health community with on-demand courses, live coaching, nutritional guidance, and rich conversations: https://neuroacademy.com/ BRAIN HEALTH INSTITUTE — our virtual clinic, offering comprehensive brain health consultations: https://brainhealthinstitute.com/ CONNECT WITH THE BRAIN DOCS: Website: https://thebraindocs.com/ Instagram: https://www.instagram.com/thebraindocs TikTok: https://www.tiktok.com/@thebraindocs </video> <video> The science of heartbreak (with Columbus Batiste, MD) Description: Cardiologist Columbus Batiste explains love’s impact on both the heart and the brain, and what the medical term for heartbreak has to do with octopi, on the ‘Your Brain On...’ podcast. In ‘Your Brain On... Love’, we discuss: • Why falling in love can feel so stressful • How being infatuated activates the same neurotransmitters as having OCD • What happens to your brain when exciting new romances settle into comfortable decades-long unions ‘Your Brain On’ is hosted by neuroscientists and public health advocates Ayesha and Dean Sherzai. ‘Your Brain On... Love’ is Episode 1 of Season 1. HEAR THE PODCAST: Apple: https://podcasts.apple.com/us/podcast/your-brain-on/id1730984252?i=1000645339130 Spotify: https://open.spotify.com/episode/762nqkVNqW4C41NkB6wxbR?si=6c1644aff74d42ca Website (and Crossword): https://thebraindocs.com/your-brain-on/love/ The ‘Your Brain On’ podcast is supported by... NEURO ACADEMY — an online brain health community with on-demand courses, live coaching, nutritional guidance, and rich conversations: https://neuroacademy.com/ BRAIN HEALTH INSTITUTE — our virtual clinic, offering comprehensive brain health consultations: https://brainhealthinstitute.com/ CONNECT WITH THE BRAIN DOCS: Website: https://thebraindocs.com/ Instagram: https://www.instagram.com/thebraindocs TikTok: https://www.tiktok.com/@thebraindocs </video> <video> Ozempic: the controversial medication, explained (with Dr. Spencer Nadolsky) Description: The past, future, risks, and benefits of Ozempic, explained by obesity and lipid specialist physician Dr. Spencer Nadolsky on the ‘Your Brain On...’ podcast. 0:00 A brief history of Ozempic 1:03 Why some people don’t respond to Ozmepic 1:46 The risks and side-effects of Ozempic 3:03 The cardiovascular benefits of Ozempic 5:15 Hollywood and weight loss stigmas In ‘Your Brain On... Ozempic’, we discuss: • The origins of Ozempic and its predecessors • How GLP-1 receptor drugs like Ozempic regulate appetite • What the latest research and trials say about Ozempic’s effects (good and bad) • Why we should quell the stigma borne from Ozempic’s brushes with celebrity culture • Where studies on Ozempic and similar medications are going next • How to ask your healthcare provider about Ozempic ‘Your Brain On’ is hosted by neuroscientists and public health advocates Ayesha and Dean Sherzai. ‘Your Brain On... Ozempic’ is Episode 10 of Season 2. HEAR THE PODCAST: Apple: https://podcasts.apple.com/podcast/your-brain-on-ozempic/id1730984252?i=1000661008470 Spotify: https://open.spotify.com/episode/3ENUhVbtCcmavAtNMkhrNe?si=CfN7Z6WjSOmwEFv6BwGxCw Website (and Crossword): https://thebraindocs.com/your-brain-on/ozempic/ The ‘Your Brain On’ podcast is supported by... NEURO ACADEMY — an online brain health community with on-demand courses, live coaching, nutritional guidance, and rich conversations: https://neuroacademy.com/ BRAIN HEALTH INSTITUTE — our virtual clinic, offering comprehensive brain health consultations: https://brainhealthinstitute.com/ CONNECT WITH THE BRAIN DOCS: Website: https://thebraindocs.com/ Instagram: https://www.instagram.com/thebraindocs TikTok: https://www.tiktok.com/@thebraindocs </video> <video> Roasted Butternut Squash Mac and Cheese #recipe #plantbased Description: </video> <video> Social media says I have ADHD. What do I do next? (with Nicole Lippman-Barile) Description: Nicole Lippman-Barile, clinical psychologist and known pseudoscience debunker, explains the risks of ADHD self-diagnosis in the age of social media. On ‘Your Brain On... ADHD’, she discussed: 0:00 The dangers of social media self-diagnosis 1:12 Similarities between ADHD, depression, and anxiety 2:23 How ADHD affects different demographics 3:29 The challenges of overdiagnosis and underdiagnosis of ADHD 5:03 How to seek a professional diagnosis for ADHD In the full podcast episode, we also discuss what’s distinct about the brains of people with ADHD, and explore the past, present, and future of ADHD diagnosis. The ‘Your Brain On’ podcast is supported by... NEURO ACADEMY — an online brain health community with on-demand courses, live coaching, nutritional guidance, and rich conversations: https://neuroacademy.com/ BRAIN HEALTH INSTITUTE — our virtual clinic, offering comprehensive brain health consultations: https://brainhealthinstitute.com/ ‘Your Brain On’ is hosted by neuroscientists and public health advocates Ayesha and Dean Sherzai. ‘Your Brain On... ADHD’ is Episode 6 of Season 1. HEAR THE PODCAST: Apple: https://podcasts.apple.com/us/podcast/your-brain-on/id1730984252?i=1000648176700 Spotify: https://open.spotify.com/episode/4TlFSIX4k8RkcMlXCrp1D7?si=kFwQV14mQtWEKf93WB7FqA Website (and Crossword): https://thebraindocs.com/your-brain-on/adhd/ CONNECT WITH THE BRAIN DOCS: Website: https://thebraindocs.com/ Instagram: https://www.instagram.com/thebraindocs TikTok: https://www.tiktok.com/@thebraindocs </video> <video> Managing caregiver stress (with Dr. Natali Edmonds) Description: Dr. Natali Edmonds, geropsychologist and founder of Dementia Careblazers, discusses the brain health effects of caregiver burden, and how mitigating those stresses can be beneficial for both caregivers and those they’re caring for. 0:00 Strengthening relationships with those we’re caring for 2:00 Factors contributing to caregiver burden 3:34 Mental health concerns for caregivers 6:06 Lifestyle-based self-care for caregivers 8:32 Managing the emotional complexities of caregiving In ‘Your Brain On... Caregiving’, we discuss: • How the chronic stress of caring for a loved one with a neurodegenerative disease like dementia can affect your brain • The ways we can mitigate these stresses, at the individual, family, and community levels • How self-care can help caregivers be more effective and attentive in their roles • Lifestyle interventions and meditative practices that can help alleviate the risks associated with caregiver burden • The need for better caregiver support at the socioeconomic and policy level • How emerging technologies are starting to help make caregivers’ workloads more manageable HEAR THE PODCAST: Apple: https://podcasts.apple.com/podcast/your-brain-on-caregiving/id1730984252?i=1000668279309 Spotify: https://open.spotify.com/episode/3eSHz5mS2y2N56iNCXogsz?si=UsmEktgWT6GPCkH9z334gQ ‘Your Brain On... Marijuana’ is Episode 5 of Season 3. The ‘Your Brain On’ podcast is supported by... NEURO ACADEMY — an online brain health community with on-demand courses, live coaching, nutritional guidance, and rich conversations: https://neuroacademy.com/ BRAIN HEALTH INSTITUTE — our virtual clinic, offering comprehensive brain health consultations: https://brainhealthinstitute.com/ CONNECT WITH THE BRAIN DOCS: Website: https://thebraindocs.com/ Instagram: https://www.instagram.com/thebraindocs TikTok: https://www.tiktok.com/@thebraindocs </video> <video> Must-Try Blueberry Oat Scones Recipe! Description: These scones are great for breakfast or brunch. Serve them with tea or coffee and some more almond butter and blueberry chia jam! Ingredients: - 2 1/2 cups oat flour (oats pulverized into flour, you can process rolled oats in your blender) - 1 1/2 teaspoons baking powder - 1/2 cup monk fruit sweetener or any sweetener of choice (1/4 cup maple syrup would work too) - Zest of 1 lemon - 1 cup fresh or frozen blueberries (I used frozen) - 3 tablespoons almond butter - 1/3 cup applesauce - (not filmed!) 2/3 cup unsweetened plant milk, preferably soy milk (high in protein), plus 2 tablespoons for glazing - 1 tbsp chopped fresh rosemary leaves - 1 tbsp ground flax seeds Bake at 375 F for 15 minutes. This is a variation of the spelt blueberry scone in our book, The 30 Day Alzheimer’s Solution. . . #brainhealth #wholegrains #scones #blueberries #healthyrecipes </video> <video> Parkinson’s, explained, with Michael J. Fox Foundation’s Dr. Rachel Dolhun Description: Dr. Rachel Dolhun (SVP of Medical Comms at the Michael J. Fox Foundation) explains the causes and symptoms of Parkinson’s disease, explains the distinctions from and overlaps with Alzheimer’s, and offers hope for the future. 0:00 The symptoms of Parkinson’s disease 1:04 Parkinson’s and Alzheimer’s: differences and similarities 3:47 The varied causes of Parkinson’s 6:04 Managing emotions after diagnosis 8:50 Parkinson’s: hope for the future In ‘Your Brain On... Parkinson’s’, we discuss: • The motor symptoms (e.g. cogwheel rigidity, bradykinesia) and non-motor symptoms (e.g. depression, sleep disorders) • How the industrial revolution may have brought about environmental factors which contribute to Parkinson’s • The differences and similarities between Parkinson’s and other neurodegenerative diseases, like Alzheimer’s • How Parkinson’s manifests in our brains • Why one nurse was able to detect Parkinson’s through smell • The neurogenetics of Parkinson’s, and the ethical quandaries of evolving genetic technology • Why lifestyle — nutrition, exercise, etc. — is so key to preventing and managing Parkinson’s HEAR THE PODCAST: Apple: https://podcasts.apple.com/podcast/your-brain-on/id1730984252?i=1000664567795 Spotify: https://open.spotify.com/episode/1dh1H4f47xX4UN2synra6P?si=WjU7j73zSfqBI_8vWURxGg ‘Your Brain On’ is hosted by neurologists, scientists and public health advocates Ayesha and Dean Sherzai. ‘Your Brain On... Parkinson’s’ is Episode 1 of Season 3. The ‘Your Brain On’ podcast is supported by... NEURO ACADEMY — an online brain health community with on-demand courses, live coaching, nutritional guidance, and rich conversations: https://neuroacademy.com/ BRAIN HEALTH INSTITUTE — our virtual clinic, offering comprehensive brain health consultations: https://brainhealthinstitute.com/ CONNECT WITH THE BRAIN DOCS: Website: https://thebraindocs.com/ Instagram: https://www.instagram.com/thebraindocs TikTok: https://www.tiktok.com/@thebraindocs </video> <video> Neuroscience in space, and the future of space travel (with Emily Calandrelli) Description: Emily Calandrelli, renowned science educator and engineer, joins us for ‘Your Brain On... Space Travel’, highlighting how what we learn while exploring space greatly benefits our lives down here on Earth. • How does space travel change astronauts’ mindsets? • Why do we so badly want to believe in aliens? • How is the way we do research in space changing? • Nutrition is key for our brains — is space food getting better? • What’s next for space travel? In the full podcast episode, we discuss: • How low gravity changes your brain structure, impacts your balance, and... actually might improve your sleep • The cognitive dangers of space travel, from the mania of isolation to the destructive forces of cosmic radiation • What spaceflight can teach us about neuroplasticity and cognitive decline The ‘Your Brain On’ podcast is supported by... NEURO ACADEMY — an online brain health community with on-demand courses, live coaching, nutritional guidance, and rich conversations: https://neuroacademy.com/ BRAIN HEALTH INSTITUTE — our virtual clinic, offering comprehensive brain health consultations: https://brainhealthinstitute.com/ ‘Your Brain On’ is hosted by neuroscientists and public health advocates Ayesha and Dean Sherzai. ‘Your Brain On... Space Travel’ is Episode 1 of Season 2. HEAR THE PODCAST: Apple: https://podcasts.apple.com/podcast/your-brain-on-space-travel/id1730984252?i=1000654141821 Spotify: https://open.spotify.com/episode/0sjlwug74obwPAQ2cJRVxF?si=ahfp4azASrWd6-eey8PWMA Website (and Crossword): https://thebraindocs.com/your-brain-on/space-travel/ CONNECT WITH THE BRAIN DOCS: Website: https://thebraindocs.com/ Instagram: https://www.instagram.com/thebraindocs TikTok: https://www.tiktok.com/@thebraindocs TIMESTAMPS 0:00 Intro 0:10 Astronauts’ minds (the overview effect) 0:58 Why we believe in aliens 1:32 How space research is changing 2:19 Is space food getting better? 2:52 The future of space travel </video> <video> Opportunities and risks of treating mental health with off-label medications, ft. Dr. Sanacora Description: </video> <video> Your brain on marijuana: the benefits and risks (with Dr. Daniele Piomelli) Description: Dr. Daniele Piomelli, Director of the Institute for the Study of Cannabis at the University of California, Irvine, discusses how marijuana use can help us and harm us, and explains the neurochemistry behind why cannabis affects us in the ways that it does. 0:00 How cannabis drove scientific discoveries 3:03 Why do we get ‘the munchies’? 3:57 How marijuana can benefit the brain 7:18 Using CBD: are there benefits? 7:47 Does marijuana affect your memory? In ‘Your Brain On... Marijuana’, we discuss: • The difference between the THC and CBD cannabinoids, and their unique effects on our brains • How your endocannabinoid system works, and how it’s altered under the influence of marijuana • Why one woman with a genetic mutation that affected her endocannabinoid system couldn’t feel pain • The benefits of marijuana: nausea relief, pain management, and possible uses for reducing seizure frequency and helping with mental health • The risks of marijuana: memory disorders, addiction, developmental issues, and the dangers of high-potency products that are increasingly difficult to regulate • Why we first consumed cannabis, about 12,000 years ago HEAR THE PODCAST: Apple: https://podcasts.apple.com/podcast/your-brain-on-marijuana/id1730984252?i=1000665228126 Spotify: https://open.spotify.com/episode/7tKZcqorf5f3zsKTSRMN1w?si=6QbYDsMgQweoU5NTEWbPwg ‘Your Brain On...’ is hosted by neurologists, scientists and public health advocates Ayesha and Dean Sherzai. ‘Your Brain On... Marijuana’ is Episode 2 of Season 3. The ‘Your Brain On’ podcast is supported by... NEURO ACADEMY — an online brain health community with on-demand courses, live coaching, nutritional guidance, and rich conversations: https://neuroacademy.com/ BRAIN HEALTH INSTITUTE — our virtual clinic, offering comprehensive brain health consultations: https://brainhealthinstitute.com/ CONNECT WITH THE BRAIN DOCS: Website: https://thebraindocs.com/ Instagram: https://www.instagram.com/thebraindocs TikTok: https://www.tiktok.com/@thebraindocs </video>

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Brain health for you, your family, and your community with Drs. Dean and Ayesha Sherzai, a unique husband-and-wife team on the cutting edge of brain science. Drs. Sherzai are dedicated to educating people on the simple steps to long-term health and wellness through their work as neurologists, scientists and public health advocates through online writing, videos, and books.

There is a tsunami of diseases of the brain such as Alzheimer’s, stroke and Parkinson’s disease permeating our culture. In our own communities and families, we all have known at least one person suffering from these illnesses and in many cases seen the fallout first-hand. There is no treatment for these diseases, and the emotional, financial and social burden is immense, and at this point, lifestyle interventions are the best solution for reducing dementia risk.

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